Monday, 27 May, 2019

Many Women With Early-Stage Breast Cancer Can Skip Chemo

Pancreatic cancer patients could live more than twice as long if given chemotherapy and radiation treatment before surgery Pancreatic cancer patients could live more than twice as long if given chemotherapy and radiation treatment before surgery
Gustavo Carr | 08 June, 2018, 10:41

He says breast cancer patients fall into three categories: Low-risk, which does not require chemo, high-risk - which demands the treatment, and an intermediate category they call "the grey area", where he says this new research now clarifies.

Thousands of patients diagnosed with breast cancer could avoid chemotherapy, that's according to the findings of a new study released this past weekend at the American Society of Clinical Oncology Conference in Chicago.

"The impact is tremendous", said the study leader, Dr. Joseph Sparano of Montefiore Medical Center in NY.

The scientists carried out a prospective trial, sponsored by the National Cancer Institute, involving around 10,000 women aged 18-75 years with hormone receptor-positive, human epidermal growth factor receptor 2-negative, axillary node-negative breast cancer, which accounts for approximately half of all breast cancers. "There are a number of men and women who say, 'I really don't care what you say, I am never likely to do chemo, '" and won't have the gene evaluation, she explained. He said "Oncologists have been waiting for these results, it will affect practice on Monday morning. It's a great news story". At five years, the overall survival rate was 98.0 percent for those who received hormone therapy alone and 98.1 percent for those who received both therapies, and at nine years the respective overall survival rates were 93.9 percent and 93.8 percent. Ray Lin, Scripps Medical Director of Radiation Oncology, to discuss the groundbreaking study.

Of those, 67% (6,711) received scores of 11 to 25 on the gene test, which indicated an intermediate risk of cancer recurrence.

However an estimated 25% of patients stop within two years because they can not endure the side effects, lead author Dr Sherry Shen, of the New York Presbyterian Hospital, said. The money was used to pay for the gene test, which costs more than $4,000 per person. This data adds to findings from a TAILORx analysis published in 2015 that provided prospective evidence that the gene expression test could identify women with a low risk of recurrence who could be spared chemotherapy.

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The patients affected by these new study results are those with estrogen-sensitive breast cancers who also test negative for the HER2 gene. "Towards the end, my eyes would water", she said. Others want chemo for even the smallest chance of benefit.

"I was a little relieved".

"I lost my hair".

"I think it's been well spent", Singer said of the stamp proceeds.

"If physicians had recommended she bypass chemo Depending on the chemical test,"that I Would have confessed that", she explained. research".