In the trailer, we see Norman Reedus' character carrying various objects across various terrains as well as wielding a variety of weapons.
It has been a couple of years since Hideo Kojimafirst started teasing his, at the time, new game, Death Stranding. The game features some huge Hollywood talent that also includes Guillermo del Toro and Mads Mikkelson. The other is Lindsay Wagnar who is even more mysterious, and flashes up towards the end of the trailer.
We got our first in-engine look at Death Stranding and I could just look at Norman Reedus crawling up rocks for hours.
Later in the trailer we saw a distinctly non-MGS kind of stealth gameplay, with Sam crouching low and using that odd shoulder-mounted contraption from the last trailer to keep track of semi-invisible predators.