The driver of the truck was taken into custody by police, who said they would evaluate him for driving under the influence after beer cans were found in his cabin.
The driver of the auto and the truck both remained at the scene to give NYPD officers their statements while the NYPD's Collision Investigation Squad investigate.
Dozens of bystanders rushed to Lyden's aid. "And while we have more protected lane-miles today than ever before, this preventable death underscores the need for every major street in New York City to have a safe, protected space to travel by bike".
Lyden's family and friends are said to be shocked that her trip of a lifetime came to such a tragic end.
Ms Lyden had been working at a Waurn Ponds aquatic centre for nearly two years.