The duchess is reportedly estranged from her father's family.
The couple is also preparing to welcome their first child together this spring.
The visit is the couple's first to Merseyside since they got married last May at Windsor Castle. Spokesperson Katie Baylis explained: "We haven't seen too much betting on this market for a while, but tonight all of a sudden we have seen a flurry of betting activity on the baby to a girl".
But despite Meghan being due to give birth to her and Harry's birthday in March or April, she and Harry are showing no signs of slowing down as they take on more engagements.
'This happens because the pressure inside the abdomen rises as the pregnancy progresses.
Meghan Markle has made history and sparked unprecedented change in the royal world since marrying Prince Harry last May, so it should come as no surprise that the Duchess of Sussex wanted to mix things up in Prince Harry's life as well.
Following the birth of their firstborn child, Meghan and Harry will move to Frogmore Cottage at Windsor Castle which is now being refurbished.
Meghan and Harry are out and about in Birkenhead in the north of England today.
Her decision to quit follows the departure of the duchess's personal assistant, Melissa Touabti, who left the palace past year after six months in the job.