The paperwork was filed on behalf of Loughlin and Giannulli, a designer, on Monday in US District Court in Boston.
According to documents obtained by CBS News, Loughlin and Giannulli each waived their right to appear in court for an arraignment and pleaded not guilty to each of the charges brought against them. The couple are facing money laundering and conspiracy to commit money laundering charges for allegedly paying $500,000 to get their two daughters admitted to USC as members of the crew team, a sport in which they did not participate.
The UTA-repped Loughlin and Giannulli were part of a yearlong investigation that also snared American Crime star Huffman and more than 30 other parents.
Last week, Huffman - as well as 12 other parents - agreed to plead guilty. The fraud-conspiracy charge carries a maximum sentence of 20 years in prison and substantial fines.
On April 8, federal prosecutors announced that Huffman was among 14 defendants who agreed to plead guilty in the scam that rocked elite schools, including the University of Southern California, UCLA, Georgetown, Yale, Stanford, the University of Texas, Wake Forest and the University of San Diego. "My desire to help my daughter is no excuse to break the law or engage in dishonesty".
Loughlin's representatives did not immediately respond to a request for comment by EW.
Lori Loughlin and husband Mossimo Giannulli have officially said "no way, Jose" to a plea deal. The Desperate Housewives alum, who paid $15,000 to fake her daughter's SAT scores, issued a public apology. "While federal prisons" have the reputation for being like "a country club - hence the nickname "Club Fed" - they are still grim, grimy and uncomfortable", attorney Debra Bogaards of Bogaards Law in San Francisco told Yahoo.