'So we are all at a loss, trying to figure out how this happened, ' Lockett-Slupski was quoted as saying as she stood across from the remains of the daycare center.
Valerie Lockett-Slupski, standing across the street from the fire-damaged house, told the newspaper she was the grandmother of four of the children, and that they were staying at the day care centre because their parents were working overnight.
The circumstances surrounding the fifth child who died were unclear. It was last inspected in December 2018.
Fire officials told goerie.com they were still working to determine what caused the fire on the west side of the city.
Anyone with information about the fire is asked to call Erie police Detective Sgt. Michael Hertel at 814-870-1260 or Detective David Walker at 814-870-1122.