Thursday, 02 July, 2020

China’s army gives limited approval to potential Covid-19 vaccine

China approves coronavirus drug for limited use Chinese COVID-19 vaccine shows promise in human trials: Details here
Deanna Wagner | 29 June, 2020, 19:28

The Phase 1 and 2 clinical trials of the CanSino's vaccine candidate showed it has the potential to prevent diseases caused by the coronavirus, which has killed half a million people globally, but its commercial success can not be guaranteed, the company said. The formula was developed by a combined military research unit and the biotech firm, the company said Monday.

As the world deals with the novel coronavirus pandemic, China National Biotec Group (CNBG) has announced a major milestone in the effort to develop a vaccine for the deadly respiratory disease. Now, China's Central Military Commission has approved the use of the drug by the military on June 25th for one year.

More than half of the 17 candidate vaccines identified by the World Health Organization (WHO) as being at the clinical evaluation stage involve Chinese companies or institutes.

In the middle of this month, another institute under CNBG in Wuhan announced the results of phase-1 and Phase-2 clinical trials of an inactivated Covid-19 vaccine candidate it developed. Trials started on 17 March.

"The Ad5-nCoV is now limited to military use only and its use can not be expanded to a broader vaccination range without the approval of the Logistics Support Department", CanSino said, referring to the Central Military Commission department which approved the military use of the vaccine.

The vaccine uses an adenovirus, which normally causes the common cold, as a vector.

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"We will do it at various sites with a certain degree of flexibility" so that the researchers can change rapidly as the virus moves, Fauci said.

Most of the other vaccines in the pipeline target not the whole germ but a key piece: the "spike" protein that studs the coronavirus surface and helps invade human cells.

It was not clear how widely the potential vaccine will be used within China's enormous military establishment.

Despite touting the effectiveness of the vaccine, CNBG did not share the exact results from the Phase 1/2 clinical trial, which was reportedly conducted on as many as 1,120 people.

The group appealed to the Secretary-General of the United Nations, Director-General of the World Health Organisation (WHO), as well as religious leaders, corporations and media companies to come together to ensure available COVID-19 vaccines.

None has yet been approved for commercial use.