Monday, 03 August, 2020

Coronavirus vaccine makes huge step as monkeys protected after single dose

Russia likely to approve world's first coronavirus vaccine by August 10 claims report Coronavirus vaccine
Deanna Wagner | 01 August, 2020, 13:54

The head of the Russian Direct Investment Fund, Kirill Dmitriev, has likened what he said was Russia's success in developing a vaccine to the Soviet Union's 1957 launch of Sputnik 1, the world's first satellite.

Barouch has been working on the development of a Covid-19 vaccine since January when Chinese scientists released the SARS-CoV-2 genome.

Health Minister Mikhail Murashko said the Gamaleya Institute, a state research facility in Moscow, had completed clinical trials of the vaccine and paperwork is being prepared to register it, Interfax news agency reported.

On the global front, Dr Anthony Fauci said that 250,000 people have registered on the National Institute of Heath's website to take part in experimental vaccine trials. But in a pandemic a single-shot vaccine has a significant advantage, sidestepping a lot of the logistical issues involved in getting people to come back for their second dose.

The study saw the monkeys given a panel of vaccine prototypes before being exposed to SARS-CoV-2 infection.

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Tests have shown that the vaccine promotes the creation of protective antibodies.

Of the six animals that received the optimal vaccine candidate, Ad26.COV2.S, none showed the virus in their lungs, and only one animal showed low levels of virus in nasal swabs.

"We are excited to see these pre-clinical data because they show our SARS-CoV-2 vaccine candidate generated a strong antibody response and provided protection with a single dose", said Paul Stoffels, Johnson & Johnson's chief scientific officer.

Pending clinical trial outcomes, the vaccine is on track to start a phase 3 efficacy trial in 30,000 participants in September.

"We are searching for more volunteers and if any one who is healthy, class 12th pass and between 18 and 55 years of age wants to become volunteer for clinical trials and join hands against COVID-19 can contact us on phone numbers - 8303028051 and 6388214084", Mr Chaturvedi said.