As well as making Giovani Lo Celso's move from Real Betis permanent, Spurs have also signed Sergio Reguilon, Matt Doherty, Pierre-Emile Hojbjerg, Carlos Vinicius, Joe Hart and Gareth Bale.
The 22-year-old joins Jose Mourinho's side on a five-year deal having been a long-term target for Spurs. He called the long-serving Spurs chairman Daniel Levy a "genius".
"It is a great opportunity to publicly thank my boss, my board, Mr. Levy, the structure, [head of recruitment] Steve [Hitchen] because what they did for the team was unbelievable", Mourinho said.
"I always loved playing football, and here I am".
Rodon's signing takes their reported transfer spend to a little under £100 million, less than seven months on from their initial decision to impose a 20 per cent pay cut on 550 staff members due to the financial impact of the coronavirus pandemic.