Monday, 25 January, 2021

How will SARS-CoV-2 severity change in the next decade?

Initial Report Suggests COVID-19 Immunity Could Last for Years In the future, scientists feel Covid will resemble the common cold-causing virus
Sandy Nunez | 14 January, 2021, 20:03

As a new, more infectious strain of SARS-CoV-2 spreads further from the United Kingdom and across the United States, the U.S. Food and Drug Administration (FDA) is advising that its impact on molecular tests will likely be low, with three approved tests now affected.

Countries have now shifted their focus to the acquisition of developed vaccines in efforts to stop the spread of the virus.

The model, published January 12 in Science, draws upon studies of the four common cold coronaviruses and SARS-CoV-1.

"So really, the name of the game is getting everyone exposed for the first time to the vaccine as quickly as possible", Jennie Lavine, a postdoctoral fellow at Emory University in Atlanta, who led the study, told the New York Times.

The researchers noted that four common cold-causing coronaviruses have been circulating in humans for a long time and nearly everyone is infected at a young age.

China's 2020 copper imports hit record high
The election of Joe Biden to succeed President Donald Trump has raised questions about the future of Trump's fight with Beijing. China posted a trade surplus of $78.17 billion in December - the highest reading on Refinitiv records going back to 2007.

Though Covid-19 is considered to primarily be a respiratory disease, SARS-CoV-2 can infect many other organs in the body.

Here we discuss SARS-CoV-2 life cycle and a number of approaches aiming to suppress viral infection rates or propagation; increase virus antigen presentation in order to activate a robust and durable adaptive immune response from the host, and/or mitigate the ARDS-related "cytokine storm" and collateral tissue damage that triggers the severe life-threatening complications of COVID-19. To address this question, Iwasaki and her colleagues analyzed the ability of SARS-CoV-2 to invade human brain organoids. Their analysis of the immunological and epidemiological data for these viruses helped them develop a model to predict the trajectory of SARS-CoV-2 as it becomes endemic.

The now available data suggests that reinfection rarely occurs within 90 days of the first (initial) infection. Targeted vaccination in vulnerable subpopulations may still save lives, they say. But if primary infections become severe in children, as in the case of more deadly but contained coronaviruses such as MERS, childhood vaccinations should be continued.

Because of those similarities, the researchers believe that the new coronavirus could also become endemic and have a far-less significant health effect on individuals who contract it after immunity is gained, becoming a virus that causes no more than common cold symptoms like the sniffles.